Melanotan II

Melanotan II is a synthetic cyclic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH), widely studied for its interaction with the melanocortin receptor family, particularly MC1R, MC3R, and MC4R. As a research compound, Melanotan II peptide is valued for its role in activating these receptor subtypes, enabling investigations into diverse physiological responses.
 
In experimental contexts:
 
MC1R activation in melanocytes has been shown to stimulate melanin synthesis, contributing to pigmentation studies.
Interactions with MC3R and MC4R are of interest in research exploring appetite regulation, metabolic signaling, and neuroendocrine functions.
The compound's cyclic structure confers unique binding dynamics compared to linear peptides, influencing its stability and receptor affinity during in vitro research.