Melanotan I

 
Melanotan I (Afamelanotide) is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), offered here in melanotan 10mg vials for qualified research applications. This melanotan I peptide selectively binds to melanocortin receptors, with a high affinity for MC1R, which is expressed in melanocytes.
In in vitro studies, activation of MC1R by Melanotan I has been shown to enhance melanin production, particularly eumelanin, by upregulating tyrosinase activity—a key enzyme in melanin biosynthesis. This peptide's ability to trigger pigmentation pathways makes it of interest in dermatological and photoprotective research.
Additionally, preclinical data suggest broader roles for Melanotan I across the melanocortin receptor family, potentially impacting appetite regulation, energy homeostasis, and metabolic signaling, though these effects remain under investigation in controlled laboratory environments.